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C-Jun N-terminal kinase inhibitors: Structural insight into kinase-inhibitor complexes

The activation of c-Jun N-terminal kinases (JNKs) plays an important role in physiological processes including neuronal function, immune activity, and development, and thus, JNKs have been a therapeutic target for various diseases such as neurodegenerative diseases, inflammation, and cancer. Efforts...

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Bibliographic Details
Published in:Comput Struct Biotechnol J
Main Authors: Duong, Men Thi Hoai, Lee, Joon-Hwa, Ahn, Hee-Chul
Format: Artigo
Language:Inglês
Published: Research Network of Computational and Structural Biotechnology 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327381/
https://ncbi.nlm.nih.gov/pubmed/32637042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.06.013
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