The effects of single versus combined therapy using LIM-kinase 2 inhibitor and type 5 phosphodiesterase inhibitor on erectile function in a rat model of cavernous nerve injury-induced erectile dysfunction

We aimed to determine whether combination of LIM-kinase 2 inhibitor (LIMK2i) and phosphodiesterase type-5 inhibitor (PDE5i) could restore erectile function through suppressing cavernous fibrosis and improving cavernous apoptosis in a rat model of cavernous nerve crush injury (CNCI). Seventy 12-week-...

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Bibliografiske detaljer
Udgivet i:Asian J Androl
Main Authors: Cho, Min Chul, Lee, Junghoon, Park, Juhyun, Oh, Sohee, Chai, Ji Sun, Son, Hwancheol, Paick, Jae-Seung, Kim, Soo Woong
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer - Medknow 2019
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732899/
https://ncbi.nlm.nih.gov/pubmed/30829289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/aja.aja_114_18
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