AB085. Improvement of erectile function through combination of anti-fibrotic effect by LIM-kinase 2 inhibitor with suppression of apoptosis and potentiation of endothelial function by type 5 phosphodiesterase inhibitor in a rat model of cavernous nerve injury

BACKGROUND: The cavernosal apoptosis and fibrosis are considered to be important pathophysiologies of post-radical prostatectomy (RP) erectile dysfunction (ED). Recently, we demonstrated that inhibition of LIMK2 alleviate ED through suppression of cavernosal fibrosis in a rat model of cavernous nerv...

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Pubblicato in:Transl Androl Urol
Autori principali: Cho, Min Chul, Song, Won Hoon, Yoo, Sangjun, Park, Juhyun, Son, Hwancheol, Paick, Jae-Seung, Kim, Soo Woong
Natura: Artigo
Lingua:Inglês
Pubblicazione: AME Publishing Company 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186709/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2018.AB085
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