Analysis of gene expression and mutation data points on contribution of transcription to the mutagenesis by APOBEC enzymes

Since the discovery of the role of the APOBEC enzymes in human cancers, the mechanisms of this type of mutagenesis remain little understood. Theoretically, targeting of single-stranded DNA by the APOBEC enzymes could occur during cellular processes leading to the unwinding of DNA double-stranded str...

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Detalhes bibliográficos
Publicado no:NAR Cancer
Main Authors: Chervova, Almira, Fatykhov, Bulat, Koblov, Alexander, Shvarov, Evgeny, Preobrazhenskaya, Julia, Vinogradov, Dmitry, Ponomarev, Gennady V, Gelfand, Mikhail S, Kazanov, Marat D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Cancer Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253550/
https://ncbi.nlm.nih.gov/pubmed/34316712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcab025
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