A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy

Recent studies have revealed that tumor cells decrease their immunogenicity by epigenetically repressing the expression of highly immunogenic antigens to survive in immunocompetent hosts. We hypothesized that these epigenetically hidden “stealth” antigens should be favorable targets for cancer immun...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancer Sci
Hlavní autoři: Kosaka, Akemi, Yajima, Yuki, Hatayama, Mayumi, Ikuta, Katsuya, Sasaki, Takaaki, Hirai, Noriko, Yasuda, Syunsuke, Nagata, Marino, Hayashi, Ryusuke, Harabuchi, Shohei, Ohara, Kenzo, Ohara, Mizuho, Kumai, Takumi, Ishibashi, Kei, Hirata‐Nozaki, Yui, Nagato, Toshihiro, Oikawa, Kensuke, Harabuchi, Yasuaki, Celis, Esteban, Okumura, Toshikatsu, Ohsaki, Yoshinobu, Kobayashi, Hiroya, Ohkuri, Takayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253266/
https://ncbi.nlm.nih.gov/pubmed/34009705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14973
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky