A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy

Recent studies have revealed that tumor cells decrease their immunogenicity by epigenetically repressing the expression of highly immunogenic antigens to survive in immunocompetent hosts. We hypothesized that these epigenetically hidden “stealth” antigens should be favorable targets for cancer immun...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kosaka, Akemi, Yajima, Yuki, Hatayama, Mayumi, Ikuta, Katsuya, Sasaki, Takaaki, Hirai, Noriko, Yasuda, Syunsuke, Nagata, Marino, Hayashi, Ryusuke, Harabuchi, Shohei, Ohara, Kenzo, Ohara, Mizuho, Kumai, Takumi, Ishibashi, Kei, Hirata‐Nozaki, Yui, Nagato, Toshihiro, Oikawa, Kensuke, Harabuchi, Yasuaki, Celis, Esteban, Okumura, Toshikatsu, Ohsaki, Yoshinobu, Kobayashi, Hiroya, Ohkuri, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253266/
https://ncbi.nlm.nih.gov/pubmed/34009705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14973
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