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Epigenetic modification augments the immunogenicity of human leukocyte antigen G serving as a tumor antigen for T cell-based immunotherapy

Tumor immune escape has been a major problem for developing effective immunotherapy. The human leukocyte antigen G (HLA-G) is a non-classical MHC class I molecule whose primary function is to protect the fetus from the mother's immune system. While HLA-G is hardly found in normal adult tissues,...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Ishibashi, Kei, Kumai, Takumi, Ohkuri, Takayuki, Kosaka, Akemi, Nagato, Toshihiro, Hirata, Yui, Ohara, Kenzo, Oikawa, Kensuke, Aoki, Naoko, Akiyama, Naoko, Sado, Masatoshi, Kitada, Masahiro, Harabuchi, Yasuaki, Celis, Esteban, Kobayashi, Hiroya
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938368/
https://ncbi.nlm.nih.gov/pubmed/27471649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1169356
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