PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) originates from squamous epithelium of the upper aerodigestive tract and is the most common malignancy in the head and neck region. Among HNSCCs, oropharynx squamous cell carcinoma (OSCC) has a unique profile and is associated with human papi...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Hirata-Nozaki, Yui, Ohkuri, Takayuki, Ohara, Kenzo, Kumai, Takumi, Nagata, Marino, Harabuchi, Shohei, Kosaka, Akemi, Nagato, Toshihiro, Ishibashi, Kei, Oikawa, Kensuke, Aoki, Naoko, Ohara, Mizuho, Harabuchi, Yasuaki, Uno, Yuji, Takei, Hidehiro, Celis, Esteban, Kobayashi, Hiroya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585001/
https://ncbi.nlm.nih.gov/pubmed/31221178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1957-5
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