PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) originates from squamous epithelium of the upper aerodigestive tract and is the most common malignancy in the head and neck region. Among HNSCCs, oropharynx squamous cell carcinoma (OSCC) has a unique profile and is associated with human papi...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Hirata-Nozaki, Yui, Ohkuri, Takayuki, Ohara, Kenzo, Kumai, Takumi, Nagata, Marino, Harabuchi, Shohei, Kosaka, Akemi, Nagato, Toshihiro, Ishibashi, Kei, Oikawa, Kensuke, Aoki, Naoko, Ohara, Mizuho, Harabuchi, Yasuaki, Uno, Yuji, Takei, Hidehiro, Celis, Esteban, Kobayashi, Hiroya
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585001/
https://ncbi.nlm.nih.gov/pubmed/31221178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1957-5
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