Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasiveness

Telomerase reverse transcriptase (TERT) maintains telomere homeostasis, thus ensuring chromosome stability and cell proliferation. In addition, several telomere‐independent functions of human TERT have been described. In this study, we report that TERT binds directly to the TCF binding elements loca...

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Sparad:
Bibliografiska uppgifter
I publikationen:Mol Oncol
Huvudupphovsmän: Bernabé‐García, Manuel, Martínez‐Balsalobre, Elena, García‐Moreno, Diana, García‐Castillo, Jesús, Revilla‐Nuin, Beatriz, Blanco‐Alcaina, Elena, Mulero, Victoriano, Alcaraz‐Pérez, Francisca, Cayuela, María L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253104/
https://ncbi.nlm.nih.gov/pubmed/33713376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12943
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