Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasiveness

Telomerase reverse transcriptase (TERT) maintains telomere homeostasis, thus ensuring chromosome stability and cell proliferation. In addition, several telomere‐independent functions of human TERT have been described. In this study, we report that TERT binds directly to the TCF binding elements loca...

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Gardado en:
Detalles Bibliográficos
Publicado en:Mol Oncol
Main Authors: Bernabé‐García, Manuel, Martínez‐Balsalobre, Elena, García‐Moreno, Diana, García‐Castillo, Jesús, Revilla‐Nuin, Beatriz, Blanco‐Alcaina, Elena, Mulero, Victoriano, Alcaraz‐Pérez, Francisca, Cayuela, María L.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253104/
https://ncbi.nlm.nih.gov/pubmed/33713376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12943
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