Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasiveness

Telomerase reverse transcriptase (TERT) maintains telomere homeostasis, thus ensuring chromosome stability and cell proliferation. In addition, several telomere‐independent functions of human TERT have been described. In this study, we report that TERT binds directly to the TCF binding elements loca...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Bernabé‐García, Manuel, Martínez‐Balsalobre, Elena, García‐Moreno, Diana, García‐Castillo, Jesús, Revilla‐Nuin, Beatriz, Blanco‐Alcaina, Elena, Mulero, Victoriano, Alcaraz‐Pérez, Francisca, Cayuela, María L.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253104/
https://ncbi.nlm.nih.gov/pubmed/33713376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12943
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