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Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes
Xist is the master regulator of X-Chromosome Inactivation (XCI), the mammalian dosage compensation mechanism that silences one of the two X chromosomes in a female cell. XCI is established during early embryonic development. Xist transgene (Tg) integrated into an autosome can induce transcriptional...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8250153/ https://ncbi.nlm.nih.gov/pubmed/34222260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.693154 |
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