Genetic Deletion of mGlu3 Metabotropic Glutamate Receptors Amplifies Ischemic Brain Damage and Associated Neuroinflammation in Mice

Backgroud: Type-3 metabotropic glutamate (mGlu3) receptors are found in both neurons and glial cells and regulate synaptic transmission, astrocyte function, and microglial reactivity. Here we show that the genetic deletion of mGlu3 receptors amplifies ischemic brain damage and associated neuroinflam...

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Detaylı Bibliyografya
Yayımlandı:Front Neurol
Asıl Yazarlar: Mastroiacovo, Federica, Zinni, Manuela, Mascio, Giada, Bruno, Valeria, Battaglia, Giuseppe, Pansiot, Julien, Imbriglio, Tiziana, Mairesse, Jerome, Baud, Olivier, Nicoletti, Ferdinando
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Neurology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248796/
https://ncbi.nlm.nih.gov/pubmed/34220677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.668877
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