Genetic Deletion of mGlu3 Metabotropic Glutamate Receptors Amplifies Ischemic Brain Damage and Associated Neuroinflammation in Mice

Backgroud: Type-3 metabotropic glutamate (mGlu3) receptors are found in both neurons and glial cells and regulate synaptic transmission, astrocyte function, and microglial reactivity. Here we show that the genetic deletion of mGlu3 receptors amplifies ischemic brain damage and associated neuroinflam...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Mastroiacovo, Federica, Zinni, Manuela, Mascio, Giada, Bruno, Valeria, Battaglia, Giuseppe, Pansiot, Julien, Imbriglio, Tiziana, Mairesse, Jerome, Baud, Olivier, Nicoletti, Ferdinando
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248796/
https://ncbi.nlm.nih.gov/pubmed/34220677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.668877
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