Pharmacologic effects of oseltamivir in immunocompromised adult patients as assessed by population PK/PD analysis and drug‐disease modelling for dosing regimen optimization

AIM: Pharmacologic effects were analysed to determine a dose recommendation for oseltamivir in immunocompromised (IC) adults with influenza. METHODS: Quantitative clinical pharmacology methods were applied to data from 160 adult IC patients (aged 18‐78 years) from two studies (NV20234, 150 patients;...

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Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Sturm, Stefan, Lemenuel‐Diot, Annabelle, Patel, Kashyap, Gibiansky, Leonid, Bhardwaj, Rajinder, Smith, Patrick F., Dang, Steve, Zwanziger, Elke, Nasmyth‐Miller, Clare, Ravva, Patanjali
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246794/
https://ncbi.nlm.nih.gov/pubmed/32808306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14523
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