Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies against Influenza-Pneumococcus Coinfection

Influenza pandemics and seasonal outbreaks have shown the potential of Influenza A virus (IAV) to enhance susceptibility to a secondary infection with the bacterial pathogen Streptococcus pneumoniae (Sp). The high morbidity and mortality rate revealed the poor efficacy of antiviral drugs and vaccine...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Main Authors: Boianelli, Alessandro, Sharma-Chawla, Niharika, Bruder, Dunja, Hernandez-Vargas, Esteban A.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906052/
https://ncbi.nlm.nih.gov/pubmed/27379214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2016.00060
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