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Zebrafish mbnl mutants model physical and molecular phenotypes of myotonic dystrophy
The muscleblind RNA-binding proteins (MBNL1, MBNL2 and MBNL3) are highly conserved across vertebrates and are important regulators of RNA alternative splicing. Loss of MBNL protein function through sequestration by CUG or CCUG RNA repeats is largely responsible for the phenotypes of the human geneti...
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| 出版年: | Dis Model Mech |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8246264/ https://ncbi.nlm.nih.gov/pubmed/34125183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.045773 |
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