Widespread displacement of DNA‐ and RNA‐binding factors underlies toxicity of arginine‐rich cell‐penetrating peptides

Due to their capability to transport chemicals or proteins into target cells, cell‐penetrating peptides (CPPs) are being developed as therapy delivery tools. However, and despite their interesting properties, arginine‐rich CPPs often show toxicity for reasons that remain poorly understood. Using a (...

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Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Lafarga, Vanesa, Sirozh, Oleksandra, Díaz‐López, Irene, Galarreta, Antonio, Hisaoka, Misaru, Zarzuela, Eduardo, Boskovic, Jasminka, Jovanovic, Bogdan, Fernandez‐Leiro, Rafael, Muñoz, Jaime, Stoecklin, Georg, Ventoso, Iván, Fernandez‐Capetillo, Oscar
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246256/
https://ncbi.nlm.nih.gov/pubmed/33978236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103311
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