Widespread displacement of DNA‐ and RNA‐binding factors underlies toxicity of arginine‐rich cell‐penetrating peptides

Due to their capability to transport chemicals or proteins into target cells, cell‐penetrating peptides (CPPs) are being developed as therapy delivery tools. However, and despite their interesting properties, arginine‐rich CPPs often show toxicity for reasons that remain poorly understood. Using a (...

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Publicado en:EMBO J
Main Authors: Lafarga, Vanesa, Sirozh, Oleksandra, Díaz‐López, Irene, Galarreta, Antonio, Hisaoka, Misaru, Zarzuela, Eduardo, Boskovic, Jasminka, Jovanovic, Bogdan, Fernandez‐Leiro, Rafael, Muñoz, Jaime, Stoecklin, Georg, Ventoso, Iván, Fernandez‐Capetillo, Oscar
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246256/
https://ncbi.nlm.nih.gov/pubmed/33978236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103311
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