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Structure/Function Analysis of human ZnT8 (SLC30A8): A Diabetes Risk Factor and Zinc Transporter

The human zinc transporter ZnT8 (SLC30A8) is expressed primarily in pancreatic β-cells and plays a key function in maintaining the concentration of blood glucose through its role in insulin storage, maturation and secretion. ZnT8 is an autoantigen for Type 1 diabetes (T1D) and is associated with Typ...

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Bibliografiske detaljer
Udgivet i:Curr Res Struct Biol
Main Authors: Daniels, Mark J., Jagielnicki, Maciej, Yeager, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244513/
https://ncbi.nlm.nih.gov/pubmed/34235474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crstbi.2020.06.001
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