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The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance
Recent genome-wide association studies demonstrated that common variants of solute carrier family 30 member 8 gene (SLC30A8) increase susceptibility to type 2 diabetes. SLC30A8 encodes zinc transporter-8 (ZnT8), which delivers zinc ion from the cytoplasm into insulin granules. Although it is well kn...
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784536/ https://ncbi.nlm.nih.gov/pubmed/24051378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68807 |
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