Impact of Oxidative Stress and Peroxisome Proliferator–Activated Receptor γ Coactivator-1α in Hepatic Insulin Resistance

OBJECTIVE—Recent studies identified accumulation of reactive oxygen species (ROS) as a common pathway causing insulin resistance. However, whether and how the reduction of ROS levels improves insulin resistance remains to be elucidated. The present study was designed to define this mechanism. RESEAR...

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Detalhes bibliográficos
Main Authors: Kumashiro, Naoki, Tamura, Yoshifumi, Uchida, Toyoyoshi, Ogihara, Takeshi, Fujitani, Yoshio, Hirose, Takahisa, Mochizuki, Hideki, Kawamori, Ryuzo, Watada, Hirotaka
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2008
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494675/
https://ncbi.nlm.nih.gov/pubmed/18487450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0144
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