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Combination treatment of db/db mice with exendin‐4 and gastrin preserves β‐cell mass by stimulating β‐cell growth and differentiation

Aim/Introduction:  Preservation of β‐cell mass is crucial for maintaining long‐term glucose homeostasis. Therapies based on incretin and its mimetics are expected to achieve this goal through various biological functions, particularly the restoration of β‐cell mass. Here we tested the effects of gas...

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Detalhes bibliográficos
Main Authors: Tamaki, Motoyuki, Fujitani, Yoshio, Uchida, Toyoyoshi, Hirose, Takahisa, Kawamori, Ryuzo, Watada, Hirotaka
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020718/
https://ncbi.nlm.nih.gov/pubmed/24843429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2040-1124.2010.00044.x
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