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Structural basis of elongation factor 2 switching

Archaebacterial and eukaryotic elongation factor 2 (EF-2) and bacterial elongation factor G (EF-G) are five domain GTPases that catalyze the ribosomal translocation of tRNA and mRNA. In the classical mechanism of activation, GTPases are switched on through GDP/GTP exchange, which is accompanied by t...

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Bibliografiske detaljer
Udgivet i:Curr Res Struct Biol
Main Authors: Fenwick, Michael K., Ealick, Steven E.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244253/
https://ncbi.nlm.nih.gov/pubmed/34235467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crstbi.2020.02.001
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