Increased expression of yes-associated protein/YAP and transcriptional coactivator with PDZ-binding motif/TAZ activates intestinal fibroblasts to promote intestinal obstruction in Crohn's disease

BACKGROUND: Intestinal obstruction caused by intestinal fibrosis is a common and serious complication of Crohn's disease (CD). Intestinal fibroblasts, the main effector cells mediating gastrointestinal fibrosis, are activated during chronic inflammation. However, the mechanism of fibroblast act...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Ou, Weijun, Xu, Weimin, Liu, Fangyuan, Guo, Yuegui, Huang, Zhenyu, Feng, Tienan, Liu, Chen-Ying, Du, Peng
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243379/
https://ncbi.nlm.nih.gov/pubmed/34186485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103452
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars