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Cytosolic protein quality control machinery: Interactions of Hsp70 with a network of co-chaperones and substrates

The chaperone heat shock protein 70 (Hsp70) and its network of co-chaperones serve as a central hub of cellular protein quality control mechanisms. Domain organization in Hsp70 dictates ATPase activity, ATP dependent allosteric regulation, client/substrate binding and release, and interactions with...

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Bibliografiske detaljer
Udgivet i:Exp Biol Med (Maywood)
Main Authors: Karunanayake, Chamithi, Page, Richard C
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243209/
https://ncbi.nlm.nih.gov/pubmed/33730888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370221999812
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