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Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions

Molecular recognition is integral to biological function and frequently involves preferred binding of a molecule to one of several exchanging ligand conformations in solution. In such a process the bound structure can be selected from the ensemble of interconverting ligands a priori (conformational...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Sekhar, Ashok, Velyvis, Algirdas, Zoltsman, Guy, Rosenzweig, Rina, Bouvignies, Guillaume, Kay, Lewis E
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819949/
https://ncbi.nlm.nih.gov/pubmed/29460778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32764
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