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Mapping the conformation of a client protein through the Hsp70 functional cycle

The 70 kDa heat shock protein (Hsp70) chaperone system is ubiquitous, highly conserved, and involved in a myriad of diverse cellular processes. Its function relies on nucleotide-dependent interactions with client proteins, yet the structural features of folding-competent substrates in their Hsp70-bo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Sekhar, Ashok, Rosenzweig, Rina, Bouvignies, Guillaume, Kay, Lewis E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547247/
https://ncbi.nlm.nih.gov/pubmed/26240333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508504112
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