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Cardiac Fibroblast-Specific Knockout of PGC-1α Accelerates AngII-Induced Cardiac Remodeling

Cardiac remodeling consisted of ventricular hypertrophy and interstitial fibrosis is the pathological process of many heart diseases. Fibroblasts as one of the major cells in the myocardium regulate the balance of the generation and degeneration of collagen, and these cells transform toward myofibro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Cardiovasc Med
Hauptverfasser: Chen, Hong-jin, Pan, Xiao-xi, Ding, Li-li-qiang, Ruan, Cheng-chao, Gao, Ping-jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8242582/
https://ncbi.nlm.nih.gov/pubmed/34222364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.664626
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