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Targeting the ACE2-Ang-(1–7) Pathway in Cardiac Fibroblasts to Treat Cardiac Remodeling and Heart Failure

Fibroblasts play a pivotal role in cardiac remodeling and the development of heart failure through the deposition of extra-cellular matrix (ECM) proteins and also by affecting cardiomyocyte growth and function. The renin-angiotensin system (RAS) is a key regulator of the cardiovascular system in hea...

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Autori principali: Iwata, Michikado, Cowling, Randy T., Yeo, Seon Ju, Greenberg, Barry
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085048/
https://ncbi.nlm.nih.gov/pubmed/21147120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.12.003
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