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Disruption of myofibroblastic Notch signaling attenuates liver fibrosis by modulating fibrosis progression and regression

The phenotypic transformation of hepatic myofibroblasts (MFs) is involved in the whole process of the progression and regression of liver fibrosis. Notch signaling has been demonstrated to modulate the fibrosis. In this study, we found that Notch signaling in MFs was overactivated and suppressed wit...

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Detalles Bibliográficos
Publicado en:Int J Biol Sci
Main Authors: Yue, Zhensheng, Jiang, Zijian, Ruan, Bai, Duan, Juanli, Song, Ping, Liu, Jingjing, Han, Hua, Wang, Lin
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241719/
https://ncbi.nlm.nih.gov/pubmed/34239344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.60056
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