Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

Myofibroblasts produce the fibrous scar in hepatic fibrosis. In the carbon tetrachloride (CCl(4)) model of liver fibrosis, quiescent hepatic stellate cells (HSC) are activated to become myofibroblasts. When the underlying etiological agent is removed, clinical and experimental fibrosis undergoes a r...

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Detalhes bibliográficos
Main Authors: Kisseleva, Tatiana, Cong, Min, Paik, YongHan, Scholten, David, Jiang, Chunyan, Benner, Chris, Iwaisako, Keiko, Moore-Morris, Thomas, Scott, Brian, Tsukamoto, Hidekazu, Evans, Sylvia M., Dillmann, Wolfgang, Glass, Christopher K., Brenner, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386114/
https://ncbi.nlm.nih.gov/pubmed/22566629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201840109
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