Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

Myofibroblasts produce the fibrous scar in hepatic fibrosis. In the carbon tetrachloride (CCl(4)) model of liver fibrosis, quiescent hepatic stellate cells (HSC) are activated to become myofibroblasts. When the underlying etiological agent is removed, clinical and experimental fibrosis undergoes a r...

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Detalles Bibliográficos
Main Authors: Kisseleva, Tatiana, Cong, Min, Paik, YongHan, Scholten, David, Jiang, Chunyan, Benner, Chris, Iwaisako, Keiko, Moore-Morris, Thomas, Scott, Brian, Tsukamoto, Hidekazu, Evans, Sylvia M., Dillmann, Wolfgang, Glass, Christopher K., Brenner, David A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386114/
https://ncbi.nlm.nih.gov/pubmed/22566629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201840109
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