Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis

BACKGROUND: Notch1 signalling is a stem-cell-related pathway that is essential for embryonic development, tissue regeneration and organogenesis. However, the role of Notch1 in the formation of myofibroblasts and fibrosis in kidneys following injury remains unknown. METHODS: The activity of Notch1 si...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Hong, Weilong, Zhang, Ge, Lu, Hong, Guo, Yangyang, Zheng, Shizhang, Zhu, Hengyue, Xiao, Yanyi, Papa, Akuetteh Percy David, Wu, Cunzao, Sun, Linxiao, Chen, Bicheng, Bai, Yongheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849313/
https://ncbi.nlm.nih.gov/pubmed/31718671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0455-y
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