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Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
Chronic kidney disease is a leading cause of death in the United States. Tubulointerstitial fibrosis (TIF) is considered the final common pathway leading to end-stage renal disease (ESRD). Here, we used pharmacologic, genetic, in vivo, and in vitro experiments to show that activation of the Notch pa...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964979/ https://ncbi.nlm.nih.gov/pubmed/20978353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43025 |
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