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Notch1 and Notch2 in Podocytes Play Differential Roles During Diabetic Nephropathy Development

Notch pathway activation in podocytes has been shown to play an important role in diabetic kidney disease (DKD) development; however, the receptors and ligands involved in the process have not been identified. Here, we report that conditional deletion of Notch1 in podocytes using NPHS2(cre)Notch1(fl...

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Vydáno v:Diabetes
Hlavní autoři: Sweetwyne, Mariya T., Gruenwald, Antje, Niranjan, Thiruvur, Nishinakamura, Ryuichi, Strobl, Lothar J., Susztak, Katalin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657584/
https://ncbi.nlm.nih.gov/pubmed/26293507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0260
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