Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo

The consumption of red meat is associated with an increased risk for colorectal cancer (CRC). Multiple lines of evidence suggest that heme iron as abundant constituent of red meat is responsible for its carcinogenic potential. However, the underlying mechanisms are not fully understood and particula...

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Udgivet i:Arch Toxicol
Main Authors: Seiwert, Nina, Adam, Janine, Steinberg, Pablo, Wirtz, Stefan, Schwerdtle, Tanja, Adams-Quack, Petra, Hövelmeyer, Nadine, Kaina, Bernd, Foersch, Sebastian, Fahrer, Jörg
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2021
Fag:
Genotoxicity and Carcinogenicity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241717/
https://ncbi.nlm.nih.gov/pubmed/33978766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-03064-6
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