Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo

The consumption of red meat is associated with an increased risk for colorectal cancer (CRC). Multiple lines of evidence suggest that heme iron as abundant constituent of red meat is responsible for its carcinogenic potential. However, the underlying mechanisms are not fully understood and particula...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arch Toxicol
Prif Awduron: Seiwert, Nina, Adam, Janine, Steinberg, Pablo, Wirtz, Stefan, Schwerdtle, Tanja, Adams-Quack, Petra, Hövelmeyer, Nadine, Kaina, Bernd, Foersch, Sebastian, Fahrer, Jörg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2021
Pynciau:
Genotoxicity and Carcinogenicity
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241717/
https://ncbi.nlm.nih.gov/pubmed/33978766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-03064-6
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