AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells

DNA double-strand breaks (DSBs) are critical DNA lesions, which threaten genome stability and cell survival. DSBs are directly induced by ionizing radiation (IR) and radiomimetic agents, including the cytolethal distending toxin (CDT). This bacterial genotoxin harbors a unique DNase-I-like endonucle...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cell Death Dis
Autores principales: Seiwert, Nina, Neitzel, Carina, Stroh, Svenja, Frisan, Teresa, Audebert, Marc, Toulany, Mahmoud, Kaina, Bernd, Fahrer, Jörg
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596597/
https://ncbi.nlm.nih.gov/pubmed/28837154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.418
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares