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AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells
DNA double-strand breaks (DSBs) are critical DNA lesions, which threaten genome stability and cell survival. DSBs are directly induced by ionizing radiation (IR) and radiomimetic agents, including the cytolethal distending toxin (CDT). This bacterial genotoxin harbors a unique DNase-I-like endonucle...
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| Publicado en: | Cell Death Dis |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5596597/ https://ncbi.nlm.nih.gov/pubmed/28837154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.418 |
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