Real‐life study on the pharmacokinetic of remdesivir in ICU patients admitted for severe COVID‐19 pneumonia

Remdesivir is one of the most encouraging treatments against SARS‐CoV‐2 infection. After intravenous infusion, RDV is rapidly metabolized (t (1/2) = 1 h) within the cells to its active adenosine triphosphate analogue form (GS‐443902) and then it can be found in plasma in its nucleoside analogue form...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Clin Pharmacol
Prif Awduron: Corcione, Silvia, De Nicolò, Amedeo, Montrucchio, Giorgia, Scabini, Silvia, Avataneo, Valeria, Bonetto, Chiara, Mornese Pinna, Simone, Cusato, Jessica, Canta, Francesca, Urbino, Rosario, Di Perri, Giovanni, Brazzi, Luca, De Rosa, Francesco Giuseppe, D'Avolio, Antonio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2021
Pynciau:
Short Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239594/
https://ncbi.nlm.nih.gov/pubmed/33990984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14895
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