Real‐life study on the pharmacokinetic of remdesivir in ICU patients admitted for severe COVID‐19 pneumonia

Remdesivir is one of the most encouraging treatments against SARS‐CoV‐2 infection. After intravenous infusion, RDV is rapidly metabolized (t (1/2) = 1 h) within the cells to its active adenosine triphosphate analogue form (GS‐443902) and then it can be found in plasma in its nucleoside analogue form...

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Dades bibliogràfiques
Publicat a:Br J Clin Pharmacol
Autors principals: Corcione, Silvia, De Nicolò, Amedeo, Montrucchio, Giorgia, Scabini, Silvia, Avataneo, Valeria, Bonetto, Chiara, Mornese Pinna, Simone, Cusato, Jessica, Canta, Francesca, Urbino, Rosario, Di Perri, Giovanni, Brazzi, Luca, De Rosa, Francesco Giuseppe, D'Avolio, Antonio
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Short Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239594/
https://ncbi.nlm.nih.gov/pubmed/33990984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14895
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