Development and validation of a UHPLC-MS/MS method for quantification of the prodrug remdesivir and its metabolite GS-441524: a tool for clinical pharmacokinetics of SARS-CoV-2/COVID-19 and Ebola virus disease

BACKGROUND: Remdesivir has received significant attention for its potential application in the treatment of COVID-19, caused by SARS-CoV-2. Remdesivir has already been tested for Ebola virus disease treatment and found to have activity against SARS and MERS coronaviruses. The remdesivir core contain...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Avataneo, Valeria, de Nicolò, Amedeo, Cusato, Jessica, Antonucci, Miriam, Manca, Alessandra, Palermiti, Alice, Waitt, Catriona, Walimbwa, Stephen, Lamorde, Mohammed, di Perri, Giovanni, D’Avolio, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197584/
https://ncbi.nlm.nih.gov/pubmed/32361744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa152
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados