Pharmacokinetics of remdesivir and GS-441524 in two critically ill patients who recovered from COVID-19

BACKGROUND: Remdesivir is a prodrug of the nucleoside analogue GS-441524 and is under evaluation for treatment of SARS-CoV-2-infected patients. OBJECTIVES: To evaluate the pharmacokinetics of remdesivir and GS-441524 in plasma, bronchoalveolar aspirate (BAS) and CSF in two critically ill COVID-19 pa...

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Dades bibliogràfiques
Publicat a:J Antimicrob Chemother
Autors principals: Tempestilli, Massimo, Caputi, Priscilla, Avataneo, Valeria, Notari, Stefania, Forini, Olindo, Scorzolini, Laura, Marchioni, Luisa, Ascoli Bartoli, Tommaso, Castilletti, Concetta, Lalle, Eleonora, Capobianchi, Maria R, Nicastri, Emanuele, D’Avolio, Antonio, Ippolito, Giuseppe, Agrati, Chiara
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337789/
https://ncbi.nlm.nih.gov/pubmed/32607555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa239
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