Validation of a UHPLC-MS/MS Method to Quantify Twelve Antiretroviral Drugs within Peripheral Blood Mononuclear Cells from People Living with HIV

Recently, anti-HIV treatment has achieved high efficacy and tolerability. Nevertheless, few data are available about the intracellular penetration of antiretrovirals, partly due to the technical challenges related to intracellular quantification. This work aimed to validate an ultra-high performance...

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Publicado en:Pharmaceuticals (Basel)
Main Authors: De Nicolò, Amedeo, Ianniello, Alice, Ferrara, Micol, Avataneo, Valeria, Cusato, Jessica, Antonucci, Miriam, De Vivo, Elisa, Waitt, Catriona, Calcagno, Andrea, Trentalange, Alice, Muccioli, Giampiero, Bonora, Stefano, Di Perri, Giovanni, D'Avolio, Antonio
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824452/
https://ncbi.nlm.nih.gov/pubmed/33375547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14010012
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