Real‐life study on the pharmacokinetic of remdesivir in ICU patients admitted for severe COVID‐19 pneumonia

Remdesivir is one of the most encouraging treatments against SARS‐CoV‐2 infection. After intravenous infusion, RDV is rapidly metabolized (t (1/2) = 1 h) within the cells to its active adenosine triphosphate analogue form (GS‐443902) and then it can be found in plasma in its nucleoside analogue form...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Corcione, Silvia, De Nicolò, Amedeo, Montrucchio, Giorgia, Scabini, Silvia, Avataneo, Valeria, Bonetto, Chiara, Mornese Pinna, Simone, Cusato, Jessica, Canta, Francesca, Urbino, Rosario, Di Perri, Giovanni, Brazzi, Luca, De Rosa, Francesco Giuseppe, D'Avolio, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Short Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239594/
https://ncbi.nlm.nih.gov/pubmed/33990984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14895
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