Prevention of HIV-1 TAT Protein-Induced Peripheral Neuropathy and Mitochondrial Disruption by the Antimuscarinic Pirenzepine

HIV-associated distal sensory polyneuropathy (HIV-DSP) affects about one third of people with HIV and is characterized by distal degeneration of axons. The pathogenesis of HIV-DSP is not known and there is currently no FDA-approved treatment. HIV trans-activator of transcription (TAT) is associated...

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Vydáno v:Front Neurol
Hlavní autoři: Han, May Madi, Frizzi, Katie E., Ellis, Ronald J., Calcutt, Nigel A., Fields, Jerel Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Neurology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239242/
https://ncbi.nlm.nih.gov/pubmed/34211430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.663373
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