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Repeated monitoring of corneal nerves by confocal microscopy as an index of peripheral neuropathy in type-1 diabetic rodents and the effects of topical insulin

We developed a reliable imaging and quantitative analysis method for in vivo corneal confocal microscopy in rodents and used it to determine whether models of type-1 diabetes replicate the depletion of corneal nerves reported in diabetic patients. Quantification was reproducible between observers an...

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Detalhes bibliográficos
Main Authors: Chen, Debbie K., Frizzi, Katie E., Guernsey, Lucie S., Ladt, Kelsey, Mizisin, Andrew P., Calcutt, Nigel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981941/
https://ncbi.nlm.nih.gov/pubmed/24147903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jns5.12044
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