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Topical Delivery of Muscarinic Receptor Antagonists Prevents and Reverses Peripheral Neuropathy in Female Diabetic Mice

Muscarinic antagonists promote sensory neurite outgrowth in vitro and prevent and/or reverse multiple indices of peripheral neuropathy in rodent models of diabetes, chemotherapy-induced peripheral neuropathy, and HIV protein-induced neuropathy when delivered systemically. We measured plasma concentr...

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Dettagli Bibliografici
Pubblicato in:J Pharmacol Exp Ther
Autori principali: Jolivalt, Corinne G., Frizzi, Katie E., Han, May Madi, Mota, Andre J., Guernsey, Lucie S., Kotra, Lakshmi P., Fernyhough, Paul, Calcutt, Nigel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292964/
https://ncbi.nlm.nih.gov/pubmed/32327528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.265447
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