Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice

Mounting evidence suggests that antiretroviral therapy (ART) drugs may contribute to the prevalence of HIV-associated neurological dysfunction. The HIV envelope glycoprotein (gp120) is neurotoxic and has been linked to alterations in mitochondrial function and increased inflammatory gene expression,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fields, Jerel Adam, Swinton, Mary K., Carson, Aliyah, Soontornniyomkij, Benchawanna, Lindsay, Charmaine, Han, May Madi, Frizzi, Katie, Sambhwani, Shrey, Murphy, Anne, Achim, Cristian L., Ellis, Ronald J., Calcutt, Nigel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868155/
https://ncbi.nlm.nih.gov/pubmed/31748578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53466-x
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