Investigation of an ALDH1A1-specific inhibitor for suppression of weight gain in a diet induced mouse model of obesity

BACKGROUND: Retinoic acid (RA) controls diverse physiological functions including weight regulation and energy metabolism. It has been reported that mice lacking ALDH1A1, one of the aldehyde dehydrogenases (ALDH) that synthesize RA, are healthy and resistant to weight gain, raising the possibility t...

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Detalhes bibliográficos
Publicado no:Int J Obes (Lond)
Main Authors: Haenisch, Michael, Ngyuen, Tai, Fihn, Conrad A., Goldstein, Alex S., Amory, John K., Treuting, Piper, Brabb, Thea, Paik, Jisun
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238815/
https://ncbi.nlm.nih.gov/pubmed/33934107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-021-00818-1
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