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Engineering cellular metabolite transport for biosynthesis of computationally predicted tropane alkaloid derivatives in yeast
Microbial biosynthesis of plant natural products (PNPs) can facilitate access to valuable medicinal compounds and derivatives. Such efforts are challenged by metabolite transport limitations, which arise when complex plant pathways distributed across organelles and tissues are reconstructed in unice...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8237673/ https://ncbi.nlm.nih.gov/pubmed/34140414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2104460118 |
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