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Engineering biosynthesis of the anticancer alkaloid noscapine in yeast
Noscapine is a potential anticancer drug isolated from the opium poppy Papaver somniferum, and genes encoding enzymes responsible for the synthesis of noscapine have been recently discovered to be clustered on the genome of P. somniferum. Here, we reconstitute the noscapine gene cluster in Saccharom...
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| Publicat a: | Nat Commun |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935968/ https://ncbi.nlm.nih.gov/pubmed/27378283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12137 |
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